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Study Links Working Long Hours to Potentially Lasting Brain Changes

Cambridge, UK

May 16, 2025 (Updated: February 04, 2026) 1 Negative I want health & wellness updates

TheWkly Analysis

Cambridge, UK: A new study published in the journal Occupational Health & Neuroscience suggests that consistently working 50+ hours a week may alter brain function and structure over time. Researchers tracked over 2,000 participants who logged their work hours and underwent cognitive tests and brain scans. Data revealed signs of memory decline, decreased mental flexibility, and physical changes in regions related to stress response and decision-making among those regularly clocking 10- or 12-hour days. The findings fuel debates around workplace culture, with advocates pointing to flexible or reduced-hour schedules as potential preventative measures for long-term cognitive health.

What this means for you:

•	If you consistently log long hours, consider adopting stress-management routines—like mindfulness or scheduled breaks—to mitigate mental fatigue.
•	Employers might respond by promoting flexible hours or mental-health days, anticipating heightened awareness of the risks of overwork.
•	For anyone already noticing concentration lapses or burnout, seeking professional advice can help you pivot toward a healthier work-life balance.

Key Entities

• Occupational Health & Neuroscience (journal): A peer-reviewed publication focusing on workplace-related physiological and psychological studies.
• University of Cambridge: Leading the research team that conducted longitudinal cognitive assessments and brain imaging.
• Global Workplace Health Advocates: Nonprofit groups championing legislation on maximum work hours, calling for better employee wellness.

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