Phase 3 Trial Reveals 85% Efficacy for mRNA RSV Vaccine in Adults Over 60
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Researchers conducted a large phase 3 trial published in the New England Journal of Medicine, randomizing 28,000 adults aged 60 and older from 20 countries into vaccine or placebo groups in a double-blind setup. They tracked PCR-confirmed RSV cases causing severe lower respiratory tract disease over 12 months, measuring efficacy through reduced hospitalizations and robust antibody levels lasting at least six months. The mRNA vaccine showed 85% efficacy in preventing severe disease, marking a strong performance against this common winter virus. This builds on prior RSV vaccine efforts, offering potential for high-risk groups to avoid serious illness.
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Key Entities
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New England Journal of Medicine
Publisher of the phase 3 trial results.
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RSV lower respiratory tract disease
Target condition in adults aged 60+.
Bias Distribution
Multi-Perspective Analysis
Left-Leaning View
Breakthrough mRNA vaccine triumphs with 85% efficacy against severe RSV in seniors, validating the life-saving technology behind COVID vaccines and advancing public health equity.
Centrist View
Phase 3 trial demonstrates 85% efficacy for mRNA RSV vaccine in preventing severe disease among adults over 60, offering a promising new tool to reduce hospitalizations.
Right-Leaning View
mRNA RSV vaccine shows 85% efficacy in trial, but skeptics question long-term safety and pushback on rushed Big Pharma products after COVID vaccine controversies.
Source & Verification
Source: Nejm
Status: AI Processed
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